MCDB-3501 (3) Structural Methods for Biological Macromolecules

Teaches fundamental knowledge about protein structures, protein interactions and protein folding. It will discuss in detail the most common methods on how proteins and macromolecular complexes are studied, such as X-ray crystallography, NMR-spectroscopy, and electron microscopy. The course will offer about 50 percent direct teaching, 40 percent discussion of papers in a journal club style, and 10 percent hands-on practicals on software packages relevant to structural biology. Recommended prereq., MCDB 2150 or EBIO 2070 (minimum grade C-). Formerly MCDB 4501.