Calculus concepts are developed through the analysis and modeling of complex systems, ranging from gene networks and cells to populations and ecosystems. Fundamental concepts of probability and statistics are also developed through the lens of calculus. This course is similar to MATH 1300, but a greater emphasis is placed on relevance and applications in biology and other life sciences. Credit not granted for this course and MATH 1081, 1300, APPM 1350, or ECON 1088. Approved for GT-MA1. Approved for arts and sciences core curriculum: quantitative reasoning and mathematical skills. Prerequisites: Requires prerequisite course of MATH 1150 or APPM 1235 (minimum grade C-) or an ALEKS math score of 76% or greater.