Introduces basic concepts in metabolic engineering and explores modern approaches in metabolic and strain engineering. Application areas that will be discussed will include the use of metabolic engineering approaches in biofuels and biorefining as well as biopharmaceutical production. CHEN 4803 and 5803 are the same course. Prerequisites: Requires pre-requisite courses of APPM 2360 and CHEM 4731 or CHEM 4611.