Develops essential skills for performing genomic analyses, with focus on developing practical research tools. Introduces human genome and microbiome projects, Python/Sql scripting, accessing and understanding genomic data, sequence alignment and search, evolutionary models, expression data, biological networks, and macromolecular structure. Prereqs., MCDB 3135 or 3500, CSCI 3104 or CHEM 4711; coreq., CSCI 2270. Same as MCDB 5621. Credit not granted for this course and CHEM 4621 or CSCI 4317.