In this critical thinking course, students will apply their knowledge of basic biology to exploring several of the most exciting topics in biomedicine including protein folding and stress responses, nutrient sensing and balance, and signal transduction across membranes. Emphasis will be placed upon human physiology and associated human diseases including Alzheimer's disease, diabetes, and cardiovascular disease. Prereq., MCDB 3120 or 3135 or 3145 or 3500 or instructor consent. MCDB 4425 and 5425 are the same course.