Emphasis will be placed upon human physiology and associated human diseases including Alzheimer's disease, diabetes and cardiovascular disease. Fulfills MCDB scientific reasoning requirement. Same as MCDB 4425. Requisites: Restricted to graduate students only.
Explores the neurobiology, cell biology, genetics and developmental biology of the visual system. Discusses neurodegenerative and vascular diseases that lead to blindness. Students read and analyze original research articles to train scientific reasoning. Involves student-organized presentations and classroom discussion. Same as MCDB 4427. Requisites: Requires prerequisite courses of MCDB 3135 and MCDB 3145 (all minimum grade D-).
Surveys development in a range of vertebrate and invertebrate systems to reconstruct the common bilatorian ancestor, and elucidate the developmental genetic changes underlying animal diversification. Lab focuses on vertebrate embryos and explores key methods in evolutionary developmental biology including in situ hybridization, embryo microinjection, and transgenesis. Recommended prereqs., MCDB 1150 or EBIO 1210 and MCDB 2150 or EBIO 2070 (minimum grade C-). EBIO 4440, EBIO 5440, MCDB 4441, and MCDB 5441 are all the same course. Requisites: Restricted to graduate students only.
Focuses on manifestations of regulated gene expression. Studies gene regulation at multiple steps, including transcription, RNA processing, and translation. Is based on critical analysis of primary research papers. Written assignments and oral presentations are required. Same as MCDB 4471.
Provides experience with and exposure to computational and experimental methods in bioinformatics and genomics. Meets once a week. Students are expected to read original research papers, discuss findings, plan and execute data analysis in selected areas. Same as MCDB 4521
Discusses recent research on how students learn and applications to the teaching of undergraduate science courses. Conducted as an interactive workshop, in which active-engagement in learning approaches are modeled and experienced by participants. Open to undergraduate and graduate students. May be used to fulfill the pedagogical training requirement for undergraduate Learning Assistants in upper division science courses. Post-doctoral and faculty auditors are welcome to participate as regular auditors.
Explores the development of invertebrate and vertebrate organisms, emphasizing cellular, molecular, and genetic mechanisms. Focuses on conceptual understanding and experimental approaches to topics such as embryology, developmental control of gene expression in eukaryotic cells, mechanisms of differentiation and morphogenesis and developmental genetics. Same as MCDB 4650. Requisites: Restricted to graduate students only.
Introduces methodology and techniques used in biological research. Designed as a tutorial between a few students and one faculty member. Students are expected to read original research papers, discuss findings, and to plan and execute experiments in selected areas. Open only to MCDB graduate students. May be repeated up to 9 total credit hours. Requisites: Restricted to Biological Sciences (MCDB) graduate students only.
Study of recent publications in transcription and RNA processing fields. Students present and discuss recent publications. Goals are that the student will improve critical analysis of data and will learn techniques relevant to the field. Students will keep up-to-date with current literature, will lead discussions of topic of interest, and will learn good presentation skills. Requisites: Requires prerequisite courses of MCDB 5210 and MCDB 5230 (all minimum grade D-).
Cell cycle regulation is a major biological issue relevant to a number of disease states, including cancer. Surveys the current literature in the cell cycle field. Students present current publications; class participation in discussion is expected. Requisites: Requires prerequisite courses of MCDB 5210 and MCDB 5230 (all minimum grade D-).
Acquaints students with various topics not normally covered in the curriculum. Offered intermittently or upon student demand, and often presented by visiting professors. May be repeated up to 4 total credit hours. Requisites: Restricted to graduate students only.
Reviews and evaluates recent scientific literature in the field of RNA chemistry and biology, including topics in structure, catalysis, bioinformatic approaches, and control of gene expression. Primarily for graduate level presentation of special topics by students and research staff. May be repeated up to 5 total credit hours. Same as CHEM 6621. Requisites: Restricted to graduate students only.
Designed for graduate students to give oral presentations on their thesis research, field questions, respond to critiques, and present background information. May be repeated up to 3 total credit hours. Requisites: Restricted to graduate students only.
